Large clinical trial showing daily cocoa supplement (415 mg procyanidins/day) have potential to reduce cardiovascular disease events.
A review of the evidence that daily consumption of flavanols can improve cardiovascular health.
High flavanol chocolate (831 mg procyanidins/day) improved cardiovascular function in heart failure patients previously optimized to guideline-directed medication.
Dose-ranging clinical trial to identify the optimal dose for improving endothelial function. This study supports cocoa health claims in the EU and USA.
Diabetic patients showed improved endothelial function with high flavanol cocoa (709 mg procyanidins/day).
Red wines in areas of greater longevity were found to contain high levels of procyanidins.